Fig. 5From: A comparison of the local immune status between the primary and metastatic tumor in colorectal cancer: a retrospective studyThe comparison of the activation/suppression values of the primary and metastatic tumors (a: PD-1, b: CTLA4, c: ICOS, d: GITR, e: HLA-DR, f: Granzyme B, g: the PD-1/CD8 ratio, h: the FOXP3/CD4 ratio). The values of CTLA4, ICOS and GITR (activation/suppression markers) in the primary tumor were significantly higher than those in the metastatic tumor (*: p < 0.05)Back to article page