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Table 1 Clinicopathologic characteristics of studied patients before and after matching

From: Laparoscopy-assisted colectomy as an Oncologically safe alternative for patients with stage T4 Colon Cancer: a propensity-matched cohort study

 

Before matching

After matching

 

LAC (n = 303) N (%) or mean (SD)

OC (n = 126) N (%) or mean (SD)

p

LAC (n = 121) N (%) or mean (SD)

OC (n = 121) N (%) or mean (SD)

p

Age (year)

55.00 (13.75)

59.46 (14.41)

0.003

56.95 (13.91)

59.61 (14.61)

0.148

Gender (male)

188 (62.0)

80 (63.5)

0.778

76 (62.8)

81 (66.9)

0.501

BMI (Kg/m2)

22.46 (3.68)

21.70 (3.53)

0.205

22.04 (2.98)

21.62 (3.54)

0.490

Previous abdominal surgery (+)

35 (11.6)

25 (19.8)

0.024

15 (12.4)

23 (19.0)

0.158

Comorbidity

  

0.003

  

0.201

 0

227 (74.9)

76 (60.3)

 

85 (70.2)

74 (61.2)

 

 1

57 (18.8)

31 (24.6)

 

26 (21.5)

29 (24.0)

 

  ≥ 2

19 (6.3)

19 (15.1)

 

10 (8.3)

18 (14.9)

 

Neoadjuvant chemotherapy (+)

5 (1.7)

6 (4.8)

0.089

1 (0.8)

6 (5.0)

0.120

Primary tumor size (cm)

5.02 (2.17)

5.50 (2.41)

0.042

5.02 (2.09)

5.49 (2.31)

0.096

Histological differentiation

  

0.081

  

0.571

 G1~ 2

230 (76.7)

93 (72.1)

 

94 (77.7)

87 (71.9)

 

 G3

39 (13.0)

27 (20.9)

 

20 (16.5)

26 (21.5)

 

 Gx

31 (10.3)

9 (7.0)

 

7 (5.8)

8 (6.6)

 

Conversion to open surgery (+)

15 (5.0)

 

11 (9.1)

 

 Severe adhesion

5 (33.3)

 

5 (45.5)

 

 Bulky tumor

8 (53.4)

 

4 (36.4)

 

 Technical difficulties

2 (13.3)

 

2 (18.2)

 

Primary tumor location

  

0.635

  

0.235

 Caecum

7 (2.3)

5 (4.0)

 

1 (0.8)

5 (4.1)

 

 Ascending colon

72 (23.8)

31 (24.6)

 

32 (26.4)

30 (24.8)

 

 Transverse colon

78 (25.7)

37 (29.4)

 

27 (22.3)

35 (28.9)

 

 Descending colon

34 (11.2)

15 (11.9)

 

14 (11.6)

16 (13.2)

 

 Sigmoid colon

112 (37.0)

38 (30.2)

 

47 (38.8)

35 (28.9)

 

Surgical procedure

  

0.128

  

0.095

 Left colectomy

65 (21.5)

17 (13.5)

 

28 (23.1)

16 (13.2)

 

 Extended left colectomy

1 (0.3)

0 (0.0)

 

1 (0.8)

0 (0.0)

 

 Transverse colectomy

9 (3.0)

10 (7.9)

 

2 (1.7)

9 (7.4)

 

 Right colectomy

112 (37.0)

53 (42.1)

 

43 (35.5)

52 (43.0)

 

 Extended right colectomy

18 (5.9)

6 (4.8)

 

6 (5.0)

6 (5.0)

 

 Sigmoid colectomy

92 (30.4)

39 (31.0)

 

39 (32.2)

37 (30.6)

 

 Total colectomy

6 (2.0)

1 (0.8)

 

2 (1.7)

1 (0.8)

 

Multivisceral resection (+)

152 (50.2)

85 (67.5)

0.100

62 (51.2)

65 (53.7)

0.699

Clinic N stage

  

0.108

  

0.095

 cN0

169 (55.8)

70 (55.6)

 

67 (55.4)

66 (54.5)

 

 cN1

87 (28.7)

45 (35.7)

 

33 (27.3)

44 (36.4)

 

 cN2

47 (15.5)

11 (8.7)

 

21 (17.4)

11 (9.1)

 

Pathologic T stage

  

0.916

  

0.895

 pT4a

194 (64.0)

80 (63.5)

 

75 (62.0)

74 (61.2)

 

 pT4b

109 (36.0)

46 (36.5)

 

46 (38.0)

47 (38.8)

 

Pathologic N stage

  

0.961

  

0.995

 pN0

173 (57.1)

73 (57.9)

 

69 (57.0)

69 (57.0)

 

 pN1a

40 (13.2)

18 (14.3)

 

15 (12.4)

17 (14.0)

 

 pN1b

43 (14.2)

19 (15.1)

 

20 (16.5)

19 (15.7)

 

 pN2a

29 (9.6)

10 (7.9)

 

11 (9.1)

10 (8.3)

 

 pN2b

18 (5.9)

6 (4.8)

 

6 (5.0)

6 (5.0)

 

Pathologic TNM stage

  

0.988

  

0.977

 IIB

124 (40.9)

51 (40.5)

 

48 (39.7)

47 (38.8)

 

 IIC

49 (16.2)

22 (17.5)

 

21 (17.4)

22 (18.2)

 

 IIIB

45 (14.9)

19 (15.1)

 

19 (15.7)

17 (14.0)

 

 IIIC

85 (28.1)

34 (27.0)

 

33 (27.3)

35 (28.9)