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Fig. 6 | BMC Cancer

Fig. 6

From: Micro-RNA-186-5p inhibition attenuates proliferation, anchorage independent growth and invasion in metastatic prostate cancer cells

Fig. 6

Model of oncogenic miR-186-5p activity in PCa. Transient inhibition of miR-186-5p resulted in an increase in the tumor suppressor AKAP12 and down-regulation of tumorigenic β-catenin in PC-3 cells. Inhibition of miR-186-5p resulted in a reduction in pro-survival p-AKT. However, ectopic miR-186-5p expression corresponded with an elevation in p-AKT

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