Fig. 6
From: Up-regulation of ceRNA TINCR by SP1 contributes to tumorigenesis in breast cancer
miR-7-inhibition abrogated TINCR-silencing elicited tumor suppressive effect. a The relative expression of miR-7 in response to TINCR knockdown or miR-7 specific inhibitor was determined by real-time PCR in both MCF-7 and MDA-MB-468 cells. ***p < 0.001. b, c The suppressive effect on cell proliferation elicited by TINCR knockdown was relieved by miR-7 inhibition. The cell viability was monitor at 0, 24, 48 and 72 h respectively using CCK-8 assay. d Colony formation assay was performed to determine the anchorage-independent growth of indicated cells. ***p < 0.001. e The invasive capacity was assessed by Matrigel coated Transwell assay. ***p < 0.001