Fig. 3

Gene signature distinguishing 1p/19q from IDHme. The heatmap shows the expression values of 5113 differentially expressed (q-value <0.01) signature genes (rows) for 178 histologically classified oligodendrogliomas (columns). Rows are Z-score-scaled and ordered based on a hierarchical clustering of the data (dendrogram not shown). Subgroups are shown in green (1p/19q) and yellow (IDHme) with tumor grades highlighted using light (grade II) and dark (grade III) shadings. Genes that are located on chromosomal arms 1p or 19q are indicated by black lines to the left of the heatmap; other genes are in gray