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Fig. 1 | BMC Cancer

Fig. 1

From: Knockdown delta-5-desaturase in breast cancer cells that overexpress COX-2 results in inhibition of growth, migration and invasion via a dihomo-γ-linolenic acid peroxidation dependent mechanism

Fig. 1

8-HOA inhibits breast cancer cell growth and migration. a Colony formation of MDA-MB 231 and 4 T1 cells at 10 days after 8-HOA treatment (1.0 μM for 48 h) and quantification analysis; b Wound healing assay and quantification of MDA-MB-231 cells upon 8-HOA treatment (1.0 μM) for 48 h. The MDA-MB 231 cells treated with vehicle were used as control; and c Wound healing assay and quantification of 4 T1 cells upon 8-HOA treatment (1.0 μM) for 48 h. The 4 T1 cells treated with vehicle were used as control. Data represent as mean ± standard deviation (*: significant difference with p < 0.05 from n ≥ 3)

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