Fig. 5
From: CRBP-1 over-expression is associated with poor prognosis in tongue squamous cell carcinoma
Knockdown of CBRP-1 reduced the cell proliferation and invasion ability in CAL-27 and SCC-25 cells. a The relative expression levels of CRBP-1 in TSCC cell lines were evaluated by western blotting. b Immunoblotting analysis of CRBP-1 in CAL-27 and SCC-25 cells transduced with two specific shRNA. c Growth curves of CAL-27 and SCC-25 cells with knockdown of CRBP-1. Scramble (sc): the lentiviral vector with a scrambled sequence that does not target any mRNA. d Images (upper panel) and quantification (lower panel) of invaded TSCC cells treated with melatonin for 24 h were analyzed in a transwell matrix penetration assay. Scar bar: 100 μm. Data is presented as mean ± S.D. **P < 0.01 versus the corresponding control groups