Table 4 Ezrin and E-cadherin expression and their association with development of HSIL and CC
Non-SIL / LSIL | HSIL / CC | Non-SIL / LSILb | HSIL / CC | p | |
|---|---|---|---|---|---|
% (n) | % (n) | ORa | ORa (95% CI) | ||
Ezrin | |||||
Neg/Lowb | 46 (39) | 12 (5) | 1.0 | 4.61 (2.36-8.96) | < 0.001 |
Moderate | 43 (37) | 30 (12) | |||
High | 11 (9) | 58 (23) | |||
E-cadherin | |||||
Neg/Low | 31 (26) | 85 (34) | 1.0 | 6.14 (2.59-14.54) | < 0.001 |
Moderate | 56 (48) | 10 (4) | |||
Highb | 13 (11) | 5 (2) | |||
Ezrin-positive nuclei | |||||
< 50%b | 28 (24) | 10 (4) | 1.0 | 3.68 (1.89-7.17) | < 0.001 |
50-89% | 46 (39) | 17 (7) | |||
≥ 90% | 26 (22) | 73 (29) | |||