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Table 13 VOCs discriminating the headspace of lung cancer cell lines and control cell lines. Analysis of abundances of VOCS in the headspace of lung cancer, breast cancer and normal lung cell lines using GCMS-SPME. A p-value < 0.05 has been considered statistically significant

From: A study on volatile organic compounds emitted by in-vitro lung cancer cultured cells using gas sensor array and SPME-GCMS

Compounds

P-values

A549/Calu3

A549/MCF7

A549/WI38VA13

Calu3/MCF7

Calu3/WI38VA13

Decane

0.326 (↑)

0.154 (↑)

1.04E-4 (↑)

0.127 (↓)

0.016 (↑)

Propylbenzene

0.507 (↑)

0.533 (↑)

0.104 (↓)

0.988 (↓)

0.071 (↓)

Dodecane

1.67E-6 (↓)

2.23E-5 (↓)

-

0.011 (↑)

1.67E-6 (↑)

Decanal

0.001 (↑)

0.001 (↑)

0.001 (↑)

-

-

Nonanal

0.002 (↑)

0.002 (↑)

1.17E-4 (↓)

-

2.21E-4 (↓)

3, 4-Dimethylheptane

-

2.75E-4 (↓)

-

2.75E-4 (↓)

-

2, 4-DimethylUndecane

-

-

0.017 (↓)

0.017 (↓)

-

2-Ethyldodecanol

3.88E-5 (↓)

-

-

3.88E-5 (↑)

3.88E-5 (↑)

2-Ethylhexanol

3.53E-5 (↓)

-

2.47E-7 (↓)

3.53E-5 (↑)

9.40E-5 (↑)

Heneicosane

0.334 (↓)

0.002 (↑)

0.002 (↑)

3.40E-4 (↑)

3.40E-4 (↑)

  1. The (↑) and (↓) shows the trend of abundances increases and decreases in lung cancer cell line samples respectively