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Table 1 Main characteristics of the studies included in the meta-analysis

From: The effect of surgery on the survival status of patients with locally advanced cervical cancer after radiotherapy/chemoradiotherapy: a meta-analysis

Study

Country

Histology

Follow-up (months)

Stage

Chemotherapy regimen

CRT alone

CRT + surgery

Surgery type

Mazeron (2016) [17]

France

Squamous/Adenocarcinoma/Adenosquamous

39.3–75.5

IB1

Cisplatin /Carboplatin

157

54

Radical hysterectomy

IB2

IIA2

IIB

Fanfani (2016) [18]

Italy

Squamous/Adenocarcinoma

CRT: 14–127

CRT+ Surgery: 13–210

IIIA

Cisplatin

77

73

Radical hysterectomy

IIIB

Cetina (2013) [16]

Mexico

Squamous/Adenocarcinoma/Adenosquamous

3–80

IB2

Cisplatin and Gemcitabine

100

111

Radical hysterectomy

IIA2

IIB

Leguevaque (2011) [12]

France

Squamous/Adenocarcinoma

CRT: 5–64

CRT+ Surgery: 5–134

IB1

Cisplatin

44

67

Piver II extended/extrafascial hysterectomy

IB2

IIA

IIA2

IIB

IIIA

IIIB

IVA

Keys (2003) [13]

U.S.A.

Squamous/Adenocarcinoma/Adenosquamous

3.6–193.2

IB2

Cisplatin

124

132

Extrafascial

hysterectomy

Morice (2012) [15]

France

Squamous/Adenocarcinoma

4.8–69.6

IB2

Cisplatin

30

31

Laparoscopic/radical hysterectomy

IIA

IIB

Darus (2008) [19]

U.S.A.

Squamous/Adenocarcinoma/Adenosquamous

1.5–138

IB2

Cisplatin, 5FU of capecitabine

30

24

Extrafascial hysterectomy

Perez (1995) [14]

U.S.A.

Epidermoid/Adenocarcinoma/Adenosquamous

36–276

IB

no

895

227

Exploratory laparotomy

IIA

IIB

  1. Chemo chemotherapy
  2. CRT chemoradiotherapy