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Fig. 3 | BMC Cancer

Fig. 3

From: Delphinidin induced protective autophagy via mTOR pathway suppression and AMPK pathway activation in HER-2 positive breast cancer cells

Fig. 3

Delphinidin induced autophagy in BT474 cells. a Representative transmission electron microscopic images of BT474 cells treated with DMSO (0.1%) or delphinidin (60, 100, and 140 μM) for 48 h. Arrows: autophagic vacuoles. b LC3 immunofluorescence-positive dots in BT474 cells (× 400). c Expression of LC3-II protein. d Statistical analysis of the LC3-II/LC3-I ratio. e Expression of the Atg5-Atg12 conjugated protein; (f): Statistical analysis on the ratio of Atg5-Atg12/β-actin. Dp: Delphinidin. *P < 0.05 vs control group; #P < 0.05 vs Dp group

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BMC Cancer

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