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Fig. 1 | BMC Cancer

Fig. 1

From: Delphinidin induced protective autophagy via mTOR pathway suppression and AMPK pathway activation in HER-2 positive breast cancer cells

Fig. 1

Delphinidin induced apoptosis in MDA-MB-453 and BT474 cells. a: CCK-8 assay to evaluate MDA-MB-453 cell viability; (b): CCK-8 assay to evaluate BT474 cell viability; (c): Expression of TUNEL-positive MDA-MB-453 cells (× 200). d Expression of TUNEL-positive BT474 cells (× 200). e Statistical graph of TUNEL-positive MDA-MB-453 cells. f Statistical graph of TUNEL-positive BT474 cells. g Expression of protein cleaved caspase-3 and cleaved caspase-9 in MDA-MB-453 cells. Statistical analysis of the cleaved caspase/caspase ratio. h Expression of protein cleaved caspase-3 and cleaved caspase-9 in BT474 cells. Statistical analysis of the cleaved caspase/caspase ratio. Dp: Delphinidin; control: DMSO (0.1%). *P < 0.05 vs control group; #P < 0.05 vs Dp group

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