Skip to main content

Table 3 Effects of BRCA germline mutation on breast cancer end points by multivariate Cox proportional hazards analysis

From: Germline breast cancer susceptibility gene mutations and breast cancer outcomes

End Point Adjusted Hazard Ratio* (95% CI) P-value
Breast cancer recurrence or death 3.04 (1.40–6.58) 0.005
Locoregional or distant recurrence 2.70 (1.20–6.06) 0.016
Distant recurrence 2.86 (1.11–7.35) 0.029
Death 8.01 (1.44–44.7) 0.018
  1. *The hazard ratios were calculated using multivariate Cox proportional hazards model adjusted for tumor size, lymph node status, triple negative status, age of breast cancer onset, surgery type, chemotherapy, radiotherapy, and hormonal therapy