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Fig. 5 | BMC Cancer

Fig. 5

From: Bexarotene inhibits the viability of non-small cell lung cancer cells via slc10a2/PPARγ/PTEN/mTOR signaling pathway

Fig. 5

The effects of slc10a2 on expression of apoptosis related genes in A549 cells treated with bexarotene. a The expression of apoptotic related genes Bcl-2, cyclin D1, c-FLIP, caspase 3, caspase 7 in A549 cells treated with bexarotene, overexpressed slc10a2 in combination with bexarotene, slc10a2-shRNA in combination with bexarotene respectively, A549 cells without any treatment as control group. b The expression of tumor suppressor genes PTEN, P21, P53, LKB1, TSC2 in A549 cells treated with bexarotene, overexpressed slc10a2 in combination with bexarotene, slc10a2-shRNA in combination with bexarotene respectively, A549 cells without any treatment as control group. All experiments were repeated 3 times

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BMC Cancer

ISSN: 1471-2407

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