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Fig. 7 | BMC Cancer

Fig. 7

From: The DNA methylation profile of liver tumors in C3H mice and identification of differentially methylated regions involved in the regulation of tumorigenic genes

Fig. 7

Human database searches showed hypomethylation of downstream regions of MST1R and SLPI with upregulation of their expressions. RNA-seq dataset and DNA methylation dataset of 41 paired normal and tumor tissues of human livers were downloaded from TCGA. a, b Average gene expression ratio (tumor tissues/normal tissues) was calculated using 41 paired data from TCGA. *, ** Significantly different at P < 0.05, and 0.01, respectively. c The difference in DNA methylation β-value (tumor – normal) for each CpG around TSS was calculated using 41 paired data from TCGA. d The correlation between expressions of MST1R and IL33 in the HCC tissues highly expressing MST1R

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