Helicase-like transcription factor expression is associated with a poor prognosis in Non-Small-Cell Lung Cancer (NSCLC)

Table 5 Multivariate analyses of the association of HLTF expression with survival and disease-free survival

Models^a	Overall survival (OS)			Disease-free survival (DFS)
Models^a	HR	95% CI	p-value	HR	95% CI	p-value
Model 1: adjusted effect of WT HLTF (for 10 units)	1.02	0.96–1.08	0.58	1	0.94–1.06	0.94
Model 2: adjusted effect of I21R HLTF	1.01	0.9–1.13	0.84	1	0.9–1.11	0.97
Model 3: adjusted effect of HLTF WT < =20.6 & I21R > 2.23 vs. the rest	1.21	0.64–2.28	0.56	1.98	1.15–3.4	0.014

Cox proportional hazard regression model was used. A cut-off of p ≤ 0.05 was used for statistical significance
^aAll models are adjusted for age, sex, stage and histology

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