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Table 5 Multivariate analyses of the association of HLTF expression with survival and disease-free survival

From: Helicase-like transcription factor expression is associated with a poor prognosis in Non-Small-Cell Lung Cancer (NSCLC)

Modelsa Overall survival (OS) Disease-free survival (DFS)
HR 95% CI p-value HR 95% CI p-value
Model 1:
adjusted effect of WT HLTF (for 10 units)
1.02 0.96–1.08 0.58 1 0.94–1.06 0.94
Model 2:
adjusted effect of I21R HLTF
1.01 0.9–1.13 0.84 1 0.9–1.11 0.97
Model 3:
adjusted effect of HLTF WT < =20.6 & I21R > 2.23 vs. the rest
1.21 0.64–2.28 0.56 1.98 1.15–3.4 0.014
  1. Cox proportional hazard regression model was used. A cut-off of p ≤ 0.05 was used for statistical significance
  2. aAll models are adjusted for age, sex, stage and histology