Helicase-like transcription factor expression is associated with a poor prognosis in Non-Small-Cell Lung Cancer (NSCLC)

Table 2 Association of WT HLTF and I21R HLTF expressions with patient clinical characteristics

Clinical factor	Categories	n	Summary WT HLTF Median (range)	p-value	Summary I21R HLTF Median (range)	p-value
Age	Age < 65	57	20.7 (2–193)	0.63	2.1 (0.7–12.7)	0.54
Age	Age > =65	114	20.5 (1.7–240)	0.63	2.3 (0.2–14.3)	0.54
Sex	F	78	20.4 (2–121)	0.84	2.4 (0.2–8.4)	0.71
Sex	M	93	20.6 (1.7–240)	0.84	2.2 (0.6–14.3)	0.71
Stage	I	121	19.6 (1.7–240)	0.46	2.1 (0.2–14.3)	0.91
Stage	II	50	23.8 (3.5–195)	0.46	2.3 (0.6–7.6)	0.91
Histology	ADC	122	21.5 (2–240)	0.061	2.3 (0.6–14.3)	0.19
	OTH	49	17.5 (1.7–195)	0.061	2.1 (0.2–8.4)	0.19
	ADC	122	21.5 (2–240)	0.09	2.3 (0.6–14.3)	0.17
	SCC	42	17.5 (1.7–195)	0.09	2.1 (0.2–7.9)	0.17

ADC Adenocarcinoma, OTH Other histology types, SCC Squamous cell carcinoma. The Mann-Whitney test was used. A cut-off of p ≤ 0.05 was used for statistical significance

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