Skip to main content

Table 1 HLTF alterations in lung adenocarcinoma and squamous cell carcinoma

From: Helicase-like transcription factor expression is associated with a poor prognosis in Non-Small-Cell Lung Cancer (NSCLC)

  Adenocarcinoma
(n = 578)
Number of cases, n (%)
Squamous cell carcinoma
(n = 504)
Number of cases, n (%)
P-value
(Fisher test)
Mutation 13 (2.2%) 8 (1.5%) 0.5110
Copy number alterations
 Homozygous deletion 1 (0.1%) 1 (0.2%) 1.00
 Heterozygosity loss 115 (22.3%) 15 (2.9%) < 0.0001
 Diploid 268 (52.0%) 68 (13.5%) < 0.0001
 Gain 120 (23.3%) 286 (57.0%) < 0.0001
 High level of amplification 11 (2.1%) 131 (26.1%) < 0.0001
 No data 63 3  
mRNA expression level
 High expression 43 (7.5%) 141 (28.6%) < 0.0001
 Low expression 0 (0.0%) 6 (1.2%) 0.0101
Total number of altered cases
  266 (46.0%) 438 (83.0%) < 0.0001
  1. Data collected from TCGA database
\