TY - JOUR AU - Dhont, Ludovic AU - Pintilie, Melania AU - Kaufman, Ethan AU - Navab, Roya AU - Tam, Shirley AU - Burny, Arsène AU - Shepherd, Frances AU - Belayew, Alexandra AU - Tsao, Ming-Sound AU - Mascaux, Céline PY - 2018 DA - 2018/04/16 TI - Helicase-like transcription factor expression is associated with a poor prognosis in Non-Small-Cell Lung Cancer (NSCLC) JO - BMC Cancer SP - 429 VL - 18 IS - 1 AB - The relapse rate in early stage non-small cell lung cancer (NSCLC) after surgical resection is high. Prognostic biomarkers may help identify patients who may benefit from additional therapy. The Helicase-like Transcription Factor (HLTF) is a tumor suppressor, altered in cancer either by gene hypermethylation or mRNA alternative splicing. This study assessed the expression and the clinical relevance of wild-type (WT) and variant forms of HLTF RNAs in NSCLC. SN - 1471-2407 UR - https://doi.org/10.1186/s12885-018-4215-y DO - 10.1186/s12885-018-4215-y ID - Dhont2018 ER -