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Table 1 Clinicopathological features of the breast cancer patients included in the study

From: Significant association between ERCC2 and MTHR polymorphisms and breast cancer susceptibility in Moroccan population: genotype and haplotype analysis in a case-control study

Variables Cases (n = 151) Controls (n = 156) P value
  n (%) n (%)  
Age at diagnosis
 Mean (years ± SD) 43.81 ± 9.74   42.72 ± 9.29   0.316
  ≤ 40 56 37.09 72 46.15 0.107
  > 40 95 62.91 84 53.85
Family history of breast cancer
 Sporadic 91 60.3    
 Familial 60 39.7    
Laterality
 Bilateral 4 2.65    
 Unilateral 147 97.35    
Histological type
 Ductal invasive 130 86.1    
 Lobular invasive 16 10.6    
 Others 5 3.3    
Histological grade
 I 10 6.6    
 II 108 71.5    
 III 27 17.9    
 unknown 6 4    
Tumor size
 T1 24 15.9    
 T2 74 49    
 T3 16 10.6    
 T4 12 7.9    
 TX 8 5.3    
 Unknown 17 11.3    
Lymph nodes status
 N0 48 31.8    
 N+ 92 60.9    
 Unknown 11 7.3    
Metastasis status
 M0 127 84.1    
 M+ 19 12.6    
 Unknown 5 3.3    
Her-2 status
 Positive 26 17.2    
 Negative 113 74.8    
 Unknown 12 7.9    
PR status
 Positive 89 58.9    
 Negative 48 31.8    
 Unknown 14 9.3    
ER status
 Positive 107 70.9    
 Negative 36 23.8    
 Unknown 8 5.3    
TN breast cancer 22 14.6    
  1. n number of individuals (except for mean ± SD age), % percentage of individuals, SD standard deviation, Her-2 Human epidermal growth factor receptor-2, PR progesterone receptor, ER estrogen receptor, TN triple negative
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