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Table 1 Clinicopathological features of the breast cancer patients included in the study

From: Significant association between ERCC2 and MTHR polymorphisms and breast cancer susceptibility in Moroccan population: genotype and haplotype analysis in a case-control study

Variables

Cases (n = 151)

Controls (n = 156)

P value

 

n

(%)

n

(%)

 

Age at diagnosis

 Mean (years ± SD)

43.81 ± 9.74

 

42.72 ± 9.29

 

0.316

  ≤ 40

56

37.09

72

46.15

0.107

  > 40

95

62.91

84

53.85

Family history of breast cancer

 Sporadic

91

60.3

   

 Familial

60

39.7

   

Laterality

 Bilateral

4

2.65

   

 Unilateral

147

97.35

   

Histological type

 Ductal invasive

130

86.1

   

 Lobular invasive

16

10.6

   

 Others

5

3.3

   

Histological grade

 I

10

6.6

   

 II

108

71.5

   

 III

27

17.9

   

 unknown

6

4

   

Tumor size

 T1

24

15.9

   

 T2

74

49

   

 T3

16

10.6

   

 T4

12

7.9

   

 TX

8

5.3

   

 Unknown

17

11.3

   

Lymph nodes status

 N0

48

31.8

   

 N+

92

60.9

   

 Unknown

11

7.3

   

Metastasis status

 M0

127

84.1

   

 M+

19

12.6

   

 Unknown

5

3.3

   

Her-2 status

 Positive

26

17.2

   

 Negative

113

74.8

   

 Unknown

12

7.9

   

PR status

 Positive

89

58.9

   

 Negative

48

31.8

   

 Unknown

14

9.3

   

ER status

 Positive

107

70.9

   

 Negative

36

23.8

   

 Unknown

8

5.3

   

TN breast cancer

22

14.6

   
  1. n number of individuals (except for mean ± SD age), % percentage of individuals, SD standard deviation, Her-2 Human epidermal growth factor receptor-2, PR progesterone receptor, ER estrogen receptor, TN triple negative