Patients, n (%) | |
---|---|
Patients with ≥1 AE | 296 (76.9) |
Patients with ≥1 AE CTC grade ≥ 3 | 105 (27.3) |
Patients with ≥1 SAE | 112 (29.1) |
Treatment discontinuations due to AE | 107 (27.8) |
Most common AEs (frequency ≥ 5%) | |
Rash | 174 (45.2) |
Diarrhea | 87 (22.6) |
Dyspnea | 66 (17.1) |
Fatigue | 65 (16.9) |
Cough | 44 (11.4) |
Malignant neoplasm progression | 31 (8.1) |
Decreased appetite | 28 (7.3) |
Nausea | 24 (6.2) |
General physical health deterioration | 21 (5.5) |
Affected system organ class | |
Skin | 194 (50.4) |
Respiratory system | 107 (27.8) |
Gastrointestinal system | 105 (27.3) |
General disorders | 99 (25.7) |
Infections and infestations | 44 (11.4) |
Neoplasms | 40 (10.4) |
Metabolic system | 35 (9.1) |