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Table 2 Comparison of demographics of patients receiving different treatments stratified by nomogram points

From: Using nomogram of the Barcelona Clinic Liver Cancer system for treatment selection in patients with stage C hepatocellular carcinoma

Nomogram points

3–4.2 (n = 241)

 

6.7–10 (n = 545)

 

11.9–13 (n = 301)

 

15.2–18 (n = 230)

 

SR/Ablation/ TACE/ Transplant (n = 226)

Targeted/ Supportive (n = 15)

P

SR/Ablation/ TACE/ Transplant (n = 448)

Targeted/ Supportive (n = 97)

P

SR/Ablation/ TACE/ Transplant (n = 152)

Targeted/ Supportive (n = 149)

P

SR/Ablation/ TACE/ Transplant (n = 46)

Targeted/ Supportive (n = 184)

p

Age

67 ± 12

72 ± 10

0.173

65 ± 13

64 ± 15

0.878

64 ± 14

64 ± 15

0.296

59 ± 13

62 ± 13

0.113

Male (%)

166 (73)

14 (93)

0.124

340 (76)

71 (73)

0.576

117 (77)

125 (84)

0.131

36 (78)

162 (88)

0.086

HBV (%)

110 (49)

4 (27)

0.115

238 (53)

55 (57)

0.522

85 (56)

87 (58)

0.665

30 (65)

112 (61)

0.587

HCV (%)

81 (36)

7 (47)

0.399

130 (29)

24 (25)

0.397

27 (18)

33 (22)

0.341

10 (22)

37 (20)

0.806

Alcoholism (%)

47 (21)

2 (13)

0.742

99 (22)

14 (14)

0.091

41 (27)

36 (24)

0.576

12 (26)

57 (31)

0.517

CTP class A (%)

225 (100)

14 (93)

0.121

371 (83)

83 (86)

0.51

99 (65)

117 (79)

0.01

0

0

N/A

Ascites (%)

21 (9)

2 (13)

0.642

83 (19)

20 (21)

0.633

61 (40)

48 (32)

0.153

30 (65)

133 (72)

0.346

eGFR > 60 (ml/min/1.73m2)

173 (77)

5 (33)

0.001

338 (75)

71 (73)

0.642

114 (75)

111 (75)

0.92

37 (80)

144 (78)

0.747

Tumor > 5 cm

26 (12)

6 (40)

0.007

280 (63)

75 (77)

0.006

121 (80)

135 (91)

0.008

34 (74)

160 (87)

0.029

Single tumor (%)

167 (74)

8 (53)

0.084

278 (62)

53 (55)

0.175

73 (48)

81 (54)

0.272

23 (50)

89 (48)

0.843

Tumor burden 0/1/2/3

16/69/14/0

13/40/47/0

0.008

4/12/50/34

3/8/27/62

<.001

0/0/35/65

0/0/21/79

0.01

0/0/0/100

0/0/0/100

N/A

Performance status 0/1/2 (%)

17/64/19

47/33/20

0.014

35/47/18

66/21/13

<.001

0/68/32

0/69/31

0.799

30/46/24

20/48/32

0.239

Vascular invasion (%)

0

0

N/A

136 (30)

57 (59)

<.001

84 (55)

107 (72)

0.003

37 (80)

170 (92)

0.016

Metastasis/lymph node (%)

0

0

N/A

27 (6)

15 (15)

0.002

30 (20)

47 (32)

0.019

14 (30)

65 (35)

0.532

AFP > 400 ng/mL

33 (15)

3 (20)

0.475

137 (31)

50 (52)

<.001

68 (45)

92 (62)

0.003

22 (48)

115 (63)

0.07

Diabetes mellitus (%)

76 (34)

6 (40)

0.614

112 (25)

23 (24)

0.79

47 (31)

46 (31)

0.993

10 (22)

38 (21)

0.871

  1. SR surgical resection, TACE transarterial chemoembolization, CTP Child-Turcotte-Pugh, eGFR estimated glomerular filtration rate, HBV hepatitis B virus, HCV hepatitis C virus
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