The serum-based VeriStrat® test is associated with proinflammatory reactants and clinical outcome in non-small cell lung cancer patients

Table 4 Biomarker association with VeriStrat classification

Analyte	Kruskal-Wallis p-value	Mann-Whitney p-value	FDR^a
CRP	<.0001	<.0001	< 0.01
IL-6	<.0001	<.0001	< 0.01
serum amyloid A	<.0001	<.0001	< 0.01
CYFRA 21-1	0.0003	0.0005	< 0.01
IGF-II	0.0003	0.0005	< 0.01
osteopontin	0.0004	0.0006	< 0.01
ferritin	0.0010	0.0013	< 0.05
TRAIL	0.0015	0.0019	< 0.05
sNeuropilin-1	0.0079	0.0090	< 0.10
TPA	0.0101	0.0113	< 0.15
resistin	0.0110	0.0123	< 0.15
visfatin	0.0138	0.0152	< 0.15
IGF-I	0.0151	0.0166	< 0.15
sRAGE	0.0200	0.0218	< 0.15
IL-2Rα	0.0203	0.0221	< 0.15
thrombospondin-2	0.0230	0.0248	< 0.15
BMP-9	0.0242	0.0261	< 0.15
procalcitonin	0.0252	0.0271	< 0.15
sVEGFR2	0.0265	0.0285	< 0.15
IGFBP-5	0.0309	0.0330	< 0.15
IL-8	0.0312	0.0333	< 0.15
adipsin	0.0436	0.0461	< 0.20
sHer-2	0.0472	0.0497	< 0.20

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