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Table 2 Cox regression analysis for DSS in 205 patients with resectable HCC

From: The clinical implications of G1-G6 transcriptomic signature and 5-gene score in Korean patients with hepatocellular carcinoma

  Univariate analysis Multivariable analysis
   95.0% CI    95.0% CI
P-value HR Lower Upper P-value HR Lower Upper
5-gene score (poor vs. good group) 0.045 2.381 1.021 5.551 0.278 1.368 0.518 3.614
Age (> = 60 vs. <  60) 0.867 1.033 0.706 1.511     
HBV 0.593 0.813 0.380 1.737     
HCV 0.076 1.548 0.956 2.507     
NBNC 0.547 0.906 0.658 1.249     
Tumor nodules 0.000 8.697 3.846 19.665 0.000 8.411 3.263 21.68
Cirrhosis (Yes vs. No) 0.581 1.225 0.597 2.515     
VI (Yes vs. No) 0.012 2.496 1.218 5.118 0.580 1.260 0.556 2.856
Tumor size (> = 5 cm vs < 5 cm) 0.008 2.674 1.297 5.512 0.026 2.534 1.116 5.755
Edmonson Grade 0.226 1.254 0.87 1.808     
AFP level (Normal (< 20) vs. elevated) 0.092 1.956 0.896 4.272     
RB1 mutation 0.008 3.133 1.344 7.303 0.527 1.368 0.518 3.614
TP53 mutation 0.629 0.819 0.364 1.841     
CTNNB1 mutation 0.212 0.542 0.207 1.418     
  1. *VI Microvascular Invasion