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Table 2 Cox regression analysis for DSS in 205 patients with resectable HCC

From: The clinical implications of G1-G6 transcriptomic signature and 5-gene score in Korean patients with hepatocellular carcinoma

 

Univariate analysis

Multivariable analysis

  

95.0% CI

  

95.0% CI

P-value

HR

Lower

Upper

P-value

HR

Lower

Upper

5-gene score (poor vs. good group)

0.045

2.381

1.021

5.551

0.278

1.368

0.518

3.614

Age (> = 60 vs. <  60)

0.867

1.033

0.706

1.511

    

HBV

0.593

0.813

0.380

1.737

    

HCV

0.076

1.548

0.956

2.507

    

NBNC

0.547

0.906

0.658

1.249

    

Tumor nodules

0.000

8.697

3.846

19.665

0.000

8.411

3.263

21.68

Cirrhosis (Yes vs. No)

0.581

1.225

0.597

2.515

    

VI (Yes vs. No)

0.012

2.496

1.218

5.118

0.580

1.260

0.556

2.856

Tumor size (> = 5 cm vs < 5 cm)

0.008

2.674

1.297

5.512

0.026

2.534

1.116

5.755

Edmonson Grade

0.226

1.254

0.87

1.808

    

AFP level (Normal (< 20) vs. elevated)

0.092

1.956

0.896

4.272

    

RB1 mutation

0.008

3.133

1.344

7.303

0.527

1.368

0.518

3.614

TP53 mutation

0.629

0.819

0.364

1.841

    

CTNNB1 mutation

0.212

0.542

0.207

1.418

    
  1. *VI Microvascular Invasion