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Table 6 Expression of CNKSR2 relative to ER, PR and HER2 status in non-malignant and malignant breast tumors

From: Regulation of CNKSR2 protein stability by the HECT E3 ubiquitin ligase Smurf2, and its role in breast cancer progression

  Non-Malignant Malignant P-value
(n = 22) (n = 62)  
CNKSR2 ER    
no/mild no/mild 14(63.64%) 8(12.9%) < 0.001
no/mild mod/intense 3(13.64%) 0(0.00%)  
mod/intense no/mild 2(9.09%) 36(58.06%)  
mod/intense mod/intense 3(13.64%) 18(29.03%)  
CNKSR2 PR    
no/mild no/mild 14(63.64%) 8(12.9%) < 0.001
no/mild mod/intense 3(13.64%) 0(0.00%)  
mod/intense no/mild 2(9.09%) 36(58.06%)  
mod/intense mod/intense 3(13.64%) 18(29.03%)  
CNKSR2 HER2    
no/mild no/mild 14(63.64%) 3(4.84%) < 0.001
no/mild mod/intense 3(13.64%) 5(8.06%)  
mod/intense no/mild 2(9.09%) 24(38.71%)  
mod/intense mod/intense 3(13.64%) 30(48.39%)