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Table 1 Determination of the urinary tract functioning status and pretreatment eGFR of the 244 patients who underwent cisplatin-based chemotherapies

From: A comparison of nephrotoxicity between patients with a solitary-functioning kidney and those with bilateral-functioning kidneys in cisplatin-based chemotherapy for advanced urothelial carcinoma: a Japanese retrospective multi-institutional study

 

Pretreatment eGFR

≥60 mL/min/1.73m2

Pretreatment eGFR

< 60 mL/min/1.73m2

Bilateral

functioning

kidneys

(n = 83)

Solitary

functioning

kidney

(n = 36)

Bilateral

functioning

kidneys

(n = 45)

Solitary

functioning

kidney

(n = 80)

Bilateral functoinal kidneys status

 BC with bilateral intact kidneys

63 (75.9%)

–

23 (51.2%)

–

 BC with an unilateral nephrostomy

4 (4.8%)

–

9 (20.0%)

–

 UTUC without nephroureterectomy or hydronephrosis

11 (13.3%)

–

11 (24.4%)

–

 UTUC with an ipsilateral nephrostomy

2 (2.4%)

–

1 (2.2%)

–

 BC + UTUC without nephroureterectomy or hydronephrosis

3 (3.6%)

–

1 (2.2%)

–

Solitary functional kidney status

 UTUC after nephroureterectomy

–

7 (19.4%)

–

37 (46.4%)

 UTUC without nephroureterectomy with an ipsilateral

–

11 (30.5%)

–

22 (27.5%)

 UTUC in the solitary kidney without hydronephroisis

–

1 (2.7%)

–

2 (2.5%)

 UTUC in the solitary kidney with the ipsilateral nephrostomy

–

0 (0.0%)

–

1 (1.2%)

 BC with an unilateral hydroneohrosis

–

7 (19.4%)

–

5 (6.2%)

 BC with bilateral hydronephroses with unilateral nephrostomy

–

2 (5.6%)

–

8 (10.0%)

 BC with a solitary kidney

–

3 (8.4%)

–

1 (1.2%)

 BC + UTUC after an unilateral nephroureterectomy

–

3 (8.4%)

–

2 (2.5%)

 BC + UTUC with an unilateral hydronephrosis

–

2 (5.6%)

–

2 (2.5%)

  1. BC bladder cancer, UTUC upper urinary tract urothelial cancer