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Table 2 RP gene copy number alterations associated with t-SNE clusters

From: Diagnostic and prognostic implications of ribosomal protein transcript expression patterns in human cancers

Genes

Type

Location

Cohort

Cluster

Frequency

RPL19, RPL23

Amplification

17q12

BRCA

1

98.9%, 83.1%

RPL8, RPL30

Amplification

8q22

BRCA

3

100%, 97.5%

  

LIHC

3

98.8%, 98.8%

  

PRAD

2

95.1%, 97.5%

  

LUNG

1

100%, 94.3%

  

SKCM

2

94.2%, 88.5%

  

HNSC

2

93.2%, 85.3%

RPS3

Amplification

11q13

BRCA

2

100%

  

LUNG

5

90.5%

RPS16

Amplification

19q13

LUNG

6

100%

RPL13A, RPL18, RPL28, RPS5, RPS9, RPS11, RPS16, RPS19

Deletion

19q13

GBMLGG

5

98.8% - 99.4%

RPL11, RPL22, RPL5, RPS8

Deletion

1p

GBMLGG

5

97.5%

RPS24

Deletion

10q22

GBMLGG

3

90.5%

  1. Some tumor clusters were significantly associated with greater incidence of copy number alterations than other tumors from the same cancer cohorts (α <  0.01); clusters with > 90% of tumors possessing a given copy number alteration are included in this table. Cancer cohorts with no tumor clusters strongly associating with a RP copy number alteration were excluded from this table