Skip to main content

Table 1 Recurring patterns of RPT expression in tumors across cancer cohorts

From: Diagnostic and prognostic implications of ribosomal protein transcript expression patterns in human cancers

Primary Difference Co-regulated RPTs Observations
Lower expression Higher Expression Cohort Cluster
Low RPL3 RPL5, RPL10, RPL17, RPL22, RPL26, RPS23 RPL28, RPL35, RPL36, RPL38, RPLP2 THCAa 1
GBMLGG 3, 4
LIHC 2, 3
KIRC 3
THYM 2
PRAD 2, 3
PAAD 1
PCPG 1
DLBC 2
High RPL8 and RPL30 RPL10, RPL13A, RPL19, RPL21, RPL34, RPL37A, RPL4, UBA52, RPL5, RPS11, RPS12, RPS13, RPS17, RPS27A, RPS8, RPS9 RPL36A, RPL7, RPS20 BRCA 3
LIHC 3
PRAD 2
LUNG 1
SKCM 2
HNSC 2
High RPS4X RPL13, RPL23, RPL37, RPL8, RPLP1, RPS16, RPS2 RPS3A, RPL17 PRAD 1
KIRC 1
THCA 1, 2
STAD 2
LAML 1
CESC 2
High RPL13 RPL10, RPL10A, RPL26, RPL3, RPL35A, RPL41, RPL5, RPL7, RPL7A, RPS12, RPS13, RPS14, RPS15A, RPS18, RPS23, RPS27, RPS3, RPS3A, RPS4X, RPS5 RPL12, RPL13, RPL18, RPL24, RPL27A, RPL28, RPL32, RPL35, RPL36, RPL37, RPL38, RPL39, RPLP1, RPLP2, RPS15, RPS17, RPS19, RPS20, RPS24, FAU, RPS4Y1, RPS9 PRAD 3
UCEC 3
KIRC 3
  1. Four recurring patterns of expression distinguishing tumor clusters from one another were observed in multiple clusters across cancer cohorts, as shown in Figs. 2 and 3a. For each pattern, the most significant and defining RPT expression difference is listed under “primary difference.” Other significant RPT expression differences associated with these patterns are listed under “co-regulated RPTs.” “Low” and “high” expression is defined relative to other tumors within a cancer cohort. Clusters with the described pattern are listed under “observations”
  2. aWhile tumors in this cluster had relatively lower expression of RPL3, other RPTs were not co-regulated in the same manner