Skip to main content

Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Table 12 Characteristics of included studies- renal cancer

From: Associations between aspirin use and the risk of cancers: a meta-analysis of observational studies

Study source Sex Study period Source of subjects No of case No of control/cohort size Cancer site Exposure assessment Exposure Definition Adjustment for covariates Study quality
Case-control studies
 Karami S [203], 2016, US M/F 2002–2007 US Kidney Cancer Study 1187 1204 Renal-cell cancer Questionnaires Use at least once a week for 3 months or longer, at least 2 years prior to the interview 1,2,3,4,5,10,11, 27,51,52 8
 Tavani A [204], 2010, Italy M/F 1992–2004 Population from Italian areas 755 1297 Renal-cell cancer Questionnaires Use at least once a week for more than 6 months(regular) 1,2,3,5,6,7,27,55,56 7
 Gago-Dominguez M [205], 1999, US M/F 1986–1994 Patients from Los Angeles County 1204 1204 Renal-cell cancer Questionnaires Had ever taken the drug 20 or more times 3,5,10,27,57 6
 Chow WH [206], 1994, US M/F 1988–1990 Population from Minnesota 440 691 Renal-cell cancer Interviewer Use at least 2 or more times per week for 1 month or longer (regular) 1,3,10 6
 McCredie M [207], 1993, Austrilia M/F 1989–1990 The NSW Central Cancer Registry 489 523 Renal-cell cancer Questionnaires Had ever taken the drug 20 or more times 1,2,3,50,58, 7
 McCredie M [208], 1988, Austrilia M/F 1977–1982 New South Wales Central Cancer Registry 360 985 Kidney cancer Questionnaires Had taken a total of more than 0.1 kg 1,2,3,44,59,60,61 6
Cohort studies
 Karami S [203], 2016, US M/F 2002–2007 Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial 135 98,807 Renal cell carcinoma Questionnaires Use at least once per week 1,3,5,10,11,27,51 7
 Brasky TM [92], 2014, US F 1998–2010 WHI 329 141,880 Kidney cancer Questionnaires Use at both baseline and year 3 visits (consistent) 1,3,4,5, 6,10,11,17,18,19,25,26,28,29,30,31,32,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48 9
 Liu W [209], 2013, US M/F 1996–2006 AARP 884 298,468 Renal cell carcinoma Questionnaires Any use of aspirin 1,2,3,4,5,6,7,10,11,18,27,53,54 7
 Cho E [210], 2011, US F 1986–2006 NHS 153 77,525 Renal cell carcinoma Questionnaires Use aspirin ≥2 times/week(regular) 1,3,6,10,18,19,27,39 7
  M 1990–2006 HPFS 180 49,403 Renal cell carcinoma Questionnaires Use aspirin ≥2 times/week(regular) 1,3,6,10,18,19,27 9
 Jacobs EJ [98], 2007, US M/F 1992–2003 Cancer Prevention Study II Nutrition Cohort 365 146,113 Kidney cancer Questionnaires Use at least 30 “times” per month(daily use of adult-strength) 1,2,3,5,7,10,11, 15,16,17,18,20,25, 27,45 8
 Friis S [62], 2003, Denmarka M/F 1989–1997 Population from North Jutland County 67 29,470 Kidney cancer Prescription database 75–150 mg once daily(low-dose aspirin) 1,2 8
 Schreinemachers DM [63], 1994, US M/F 1971–1987 The National Health and Examination Survey Ι 32 12,668 Kidney cancer Self reported Use aspirin during the 30-day period before the interview 1,2 6
 Paganini-Hill A [103], 1989, US M/F 1981–1988 Population from Leisure World, Laguna Hills, US 25 13,870 Kidney cancer Questionnaires Aspirin use: none,<daily, daily 2 4
  1. 1 = age, 2 = sex, 3 = smoking, 4 = family history, 5 = educational level, 6 = alcohol intake, 7 = diabetes, 8 = fat distribution, 9 = social status, 10 = BMI,11 = race, 12 = folate, 13 = height, 14 = Alternate Healthy Eating Index-2010, 15 = PSA test in past 2 y, 16 = mammogram in past 2 y, 17 = hormone replacement therapy, 18 = physical activity, 19 = fruit, vegetable and/or vitamin intake, 20 = history of colonoscopy, 21 = total energy intake, 22 = ever use of calcium supplements in the past 5 years, 23 = former health checkup, 24 = red meat, 25 = other NSAIDs, 26 = area (county/region), 27 = hypertension, 28 = migraine, 29 = ever use of calcium supplements in the past 5 years, 30 = red meat, 31 = Nitro-vasodilator use, 32 = height, 33 = unique number of hospitalizations in the year prior to start of follow up, 34 = observational study enrollment, 35 = diet modification trial enrollment, 36 = screening for cancer, 37 = age at menarche, 38 = age at menopause, 39 = gravidity, 40 = age atfirst birth, 41 = duration of estrogen therapy, 42 = duration of combined postmenopausal hormone therapy, 43 = hysterectomy status, 44 = use of antihypertensive medication, 45 = history of coronary heart disease, 46 = use of cholesterol-lowering medication, 47 = history of arthritis, 48 = history of ulcer, 49 = method of interview, 50 = obesity, 51 = center, 52 = dialysis treatment, 53 = marital status, 54 = total dietary fiber, 55 = study center, 56 = year of interview, 57 = regular use of amphetamines, 58 = method of interview, 59 = phenacetin, 60 = paracetamol, 61 = urological disease
  2. AARP AARP diet and health study, HPFS Health Professionals follow-up study, NHS nurses’ health study, WHI women’s health initiative
  3. aStudy deemed to be prone to immortal time bias