Fig. 4

Effect of latrunculin A on MCF7 cancer cell clustering and calcein transfer. a Transfer of calcein during clustering from donor positive cells to negative cells incubated or not with 100 nM latrunculin A. The percentage of receiver newly positive cells is indicated. Results are the mean ± SD of 7 independent experiments. Unpaired two-tailed t-tests, **p < 0.005 at 2 h, and ***p < 0.0005 at 5 h and 10 h. b Variation of the area occupied by MCF7 cells during the clustering assay with cells incubated or not with 100 nM latrunculin A (n = 22). Results are the mean ± SD of 4 independent experiments. Unpaired two-tailed t-tests at 2 h, ***p < 0.0005