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Fig. 3 | BMC Cancer

Fig. 3

From: Gap junctions contribute to anchorage-independent clustering of breast cancer cells

Fig. 3

Effect of GJIC pharmacological inhibition on MCF7 cancer cell clustering. a Representative in-focus bright-field images are shown for each experimental condition at the indicated time points. b, c Variation of the area occupied by MCF7 cells during the clustering assay with cells incubated with: (b) tonabersat (300 μM, n = 17) or not (control) (n = 14), or (c) meclofenamate (300 μM, n = 16) or not (control) (n = 16). At 2 h, p < 0.0001. Results are the mean ± SD of 3 independent experiments. Unpaired two-tailed t-tests at 2 h, ***p < 0.005

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