Fig. 2
From: Gap junctions contribute to anchorage-independent clustering of breast cancer cells
Pharmacological inhibition of GJIC during MCF7 cancer cell clustering. Effect of incubation with (a) tonabersat (300 μM) and (b) meclofenamate (300 μM) versus control (not treated) on calcein transfer from donor positive cells to negative cells during the clustering assay. The percentage of receiver cells (negative cells that become calcein-positive) is indicated. Results are the mean ± SD of 4 independent experiments for tonabersat and 3 independent experiments for meclofenamate (3 replicates per condition in each experiment). Unpaired two-tailed t-tests, except for (b) at 10 h: Mann-Whitney non-parametric test, *p < 0.05, **p < 0.005 and ***p < 0.0005