From: Low-dose aspirin use and survival in colorectal cancer: results from a population-based cohort study
Aspirin use in first year after cancer diagnosisa | ||||
---|---|---|---|---|
Yes (n = 2150) | No (n = 6241) | |||
Number | % | Number | % | |
Age | ||||
< 50 | 13 | 0.6 | 432 | 6.9 |
50–59 | 131 | 6.1 | 1113 | 17.8 |
60–69 | 586 | 27.3 | 1973 | 31.6 |
70–79 | 934 | 43.4 | 1876 | 30.1 |
≥ 80 | 486 | 22.6 | 847 | 13.6 |
Gender | ||||
Men | 1387 | 64.5 | 3287 | 52.7 |
Deprivation (fifth) | ||||
1 (most deprived) | 447 | 20.8 | 1039 | 16.6 |
2 | 497 | 23.1 | 1272 | 20.4 |
3 | 429 | 20.0 | 1263 | 20.2 |
4 | 412 | 19.2 | 1361 | 21.8 |
5 (least deprived) | 365 | 17.0 | 1305 | 20.9 |
Tumour location | ||||
Colon | 1493 | 69.4 | 4227 | 67.7 |
Rectum/rectosigmoid junction | 657 | 30.6 | 2014 | 32.3 |
Dukes’ stage | ||||
A | 597 | 27.8 | 1683 | 27.0 |
B | 851 | 39.6 | 2340 | 37.5 |
C | 702 | 32.7 | 2218 | 35.5 |
Grade | ||||
Well differentiated | 82 | 3.8 | 203 | 3.3 |
Moderately differentiated | 1646 | 76.6 | 4796 | 76.8 |
Poorly differentiated | 315 | 14.7 | 968 | 15.5 |
Missing | 107 | 5.0 | 274 | 4.4 |
Treatment (within six months) | ||||
Surgery | 2020 | 94.0 | 5908 | 94.7 |
Radiotherapy | 192 | 8.9 | 679 | 10.9 |
Chemotherapy | 472 | 22.0 | 2167 | 34.7 |
Comorbidity before cancer diagnosis | ||||
Acute myocardial infarction | 300 | 14.0 | 103 | 1.7 |
Congestive heart failure | 135 | 6.3 | 94 | 1.5 |
Peripheral vascular disease | 145 | 6.7 | 80 | 1.3 |
Cerebral vascular accident | 162 | 7.5 | 141 | 2.3 |
Pulmonary disease | 207 | 9.6 | 383 | 6.1 |
Peptic ulcer | 59 | 2.7 | 151 | 2.4 |
Liver disease | 6 | 0.3 | 25 | 0.4 |
Diabetes | 290 | 13.5 | 285 | 4.6 |
Renal disease | 87 | 4.0 | 102 | 1.6 |
Statin use after diagnosis | 1647 | 76.6 | 1490 | 23.9 |