Fig. 3
From: Clinical decision making in the era of immunotherapy for high grade-glioma: report of four cases
MRI images of P1 at initial diagnosis (A and a), at 2 months of initiation of nivolumab when a new enhancing lesion was noted in the centrum semiovale of the left frontal lobe (B and b), at 3.5 months of initiation of nivolumab prior to biopsy showing an increase in size of the enhancing lesion and mass effect on the left lateral ventricle (C and c) and at 7 months of initiation of nivolumab prior to second craniotomy illustrating a continued increase in size of the enhancing left frontal lesion and left frontal edema (D and d)