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Table 4 ROC and LOOCV of ADC and rCBF values for differentiating MGMT (+) from MGMT (−)

From: Structural and advanced imaging in predicting MGMT promoter methylation of primary glioblastoma: a region of interest based analysis

Values

AUC

Sensitivity (%)

Specificity (%)

Cutoff value

LOOCV

Accuracy(%)

LOOCV

AUC

rCBF

0.835

75.0

78.4

7.680

74.0

0.814

ADC (×10−3 mm2/s)

0.860

81.1

82.5

0.792

79.2

0.842

  1. Note: ADC = apparent diffusion coefficient, rCBF = relative cerebral blood flow, AUC = area under ROC curve, LOOCV = leave-one-out cross-validation, MGMT (−) = MGMT promoter unmethylated, MGMT (+) = MGMT promoter methylated