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Table 4 ROC and LOOCV of ADC and rCBF values for differentiating MGMT (+) from MGMT (−)

From: Structural and advanced imaging in predicting MGMT promoter methylation of primary glioblastoma: a region of interest based analysis

Values AUC Sensitivity (%) Specificity (%) Cutoff value LOOCV
Accuracy(%)
LOOCV
AUC
rCBF 0.835 75.0 78.4 7.680 74.0 0.814
ADC (×10−3 mm2/s) 0.860 81.1 82.5 0.792 79.2 0.842
  1. Note: ADC = apparent diffusion coefficient, rCBF = relative cerebral blood flow, AUC = area under ROC curve, LOOCV = leave-one-out cross-validation, MGMT (−) = MGMT promoter unmethylated, MGMT (+) = MGMT promoter methylated