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Table 2 Correlations between MGMT status and image features

From: Structural and advanced imaging in predicting MGMT promoter methylation of primary glioblastoma: a region of interest based analysis

  Unmethylated Methylated Total P-value*
Location, n (%)     0.012
 Type I 12/48 (25) 12/44 (27) 24/92 (26)  
 Type II 16/48 (33) 4/44 (9) 20/92 (22)  
 Type III 18/48 (39) 20/ 44 (45) 38/92 (41)  
 Type IV 2/48 (4) 8 /44 (18) 10/92 (11)  
Tumor cross midline, n (%)     0.478
 No 38/48 (79) 36/44 (82) 74/92 (80)  
 Yes 10/48 (21) 8/44 (18) 18/92 (20)  
Multifocal, n (%)     0.114
 No 39/48 (81) 30/44 (68) 69/92 (75)  
 Yes 9/48 (19) 14/44 (32) 23/92 (25)  
Necrosis, n (%)     0.028
 No 2/48 (4) 0 2/92 (2)  
 Mild 26/48 (54) 15/44 (34) 41/92 (45)  
 Severe 20/48 (42) 29/44 (66) 49/92 (53)  
Cyst, n (%)     0.335
 No 40/48 (83) 39/44 (87) 79/92 (86)  
 Yes 8/48 (17) 5/44 (13) 13/92 (14)  
Edema, n (%)     0.688
 No 10/48 (21) 6/44 (14) 16/92 (17)  
 Mild 25/48 (52) 26/44 (59) 51/92 (55)  
 Severe 13/48 (27) 12/44 (27) 25/92 (28)  
Enhancement, n (%)     0.259
 Nodular 11/48 (23) 9/44 (20) 20/92 (22)  
 Patchy 7/48 (15) 2/44 (5) 9/92 (10)  
 Ringlike 30/48 (62) 33/44 (75) 63/92 (68)  
Side, n (%)     0.720
 Left 20/48 (42) 19/44 (43) 39/92 (42)  
 Right 22/48 (46) 17/44 (39) 39/92 (42)  
 Midline 6/48 (12) 8/44 (18) 14/92 (16)  
  1. Note: The P values* were calculated from the Fisher’s exact test