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Table 2 Relationship between smoking and nasopharyngeal EBV load, EBV VCA/IgA antibody

From: Lack of association between cigarette smoking and Epstein Barr virus reactivation in the nasopharynx in people with elevated EBV IgA antibody titres

Smoking characteristics No. EBV DNA copies, log10 (Mean ± SD) P valuea VCA/IgA titer, log10 (Mean ± SD) P valuea
Smoking status      
 Never smoker 37 2.87 ± 1.60 0.384 1.05 ± 0.21 0.228
 Former smoker 40 3.36 ± 1.55   1.00 ± 0.21  
 Current smoker 236 3.19 ± 1.58   1.07 ± 0.23  
P trend    0.251   0.551
 Age at smoking initiation (years)
 <  20 127 3.05 ± 1.68 0.123 1.07 ± 0.22 0.924
 20–29 123 3.29 ± 1.53   1.06 ± 0.24  
 ≥30 26 3.71 ± 1.10   1.04 ± 0.24  
 P trend    0.025   0.911
Smoking intensity (cigarettes/day)
 ≤10 51 3.27 ± 1.47 0.604 1.06 ± 0.23 0.282
 11–30 159 3.19 ± 1.62   1.07 ± 0.23  
 > 30 31 3.33 ± 1.49   1.00 ± 0.20  
 P trend    0.273   0.327
Smoking duration (years)
 ≤15 24 3.23 ± 1.54 0.551 0.99 ± 0.24 0.350
 16–30 123 3.14 ± 1.59   1.06 ± 0.22  
 > 30 129 3.29 ± 1.58   1.08 ± 0.23  
 P trend    0.224   0.240
Type of cigarettes smoked
 Filtered cigarettes 174 3.23 ± 1.56 0.635 1.07 ± 0.23 0.895
 Non-filtered cigarettes 34 3.26 ± 1.35   1.08 ± 0.24  
 Both type 68 3.15 ± 1.72   1.05 ± 0.22  
 P trend    0.392   0.926
Cumulative smoking (pack-yearsb)
 < 20 95 3.16 ± 1.53 0.202 1.03 ± 0.23 0.252
 20–39 136 3.37 ± 1.59   1.09 ± 0.24  
 ≥40 45 2.91 ± 1.58   1.04 ± 0.19  
 P trend    0.768   0.846
  1. aComparisons were performed using one-way ANOVA; b pack-years = (number of cigarettes smoked per day/20) × number of years smoked. Abbreviation: EBV, Epstein-Barr virus; VCA/IgA, IgA antibodies against viral capsid antigen; SD, standard deviation
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