TY - JOUR AU - Chen, Yufeng AU - Xu, Yifei AU - Zhao, Weilin AU - Xiao, Xue AU - Zhou, Xiaoying AU - Lin, Longde AU - Huang, Tingting AU - Liao, Jian AU - Li, Yancheng AU - Zeng, Xiaoyun AU - Huang, Guangwu AU - Ye, Weimin AU - Zhang, Zhe PY - 2018 DA - 2018/02/14 TI - Lack of association between cigarette smoking and Epstein Barr virus reactivation in the nasopharynx in people with elevated EBV IgA antibody titres JO - BMC Cancer SP - 190 VL - 18 IS - 1 AB - Subjects with elevated Epstein-Barr virus (EBV) immunoglobulin A (IgA) titers have a higher risk of developing nasopharyngeal carcinoma (NPC), indicating that reactivation of EBV in the local mucosa might be important for NPC carcinogenesis. Cigarette smoking appears to be one of the environmental risk factors for NPC. However, it remains unclear whether smoking-induced nasopharyngeal carcinogenesis acts through reactivating EBV in the nasopharyngeal mucosa. Therefore, this study aims to investigate the association between cigarette smoking and nasopharyngeal EBV reactivation in a NPC high-risk population. SN - 1471-2407 UR - https://doi.org/10.1186/s12885-018-4110-6 DO - 10.1186/s12885-018-4110-6 ID - Chen2018 ER -