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Table 2 Description of neurological adverse events (NAE)

From: High-dose thiotepa-related neurotoxicity and the role of tramadol in children

 

Patients (N = 251)

Symptoms

n

NCI CTCAE grade

1

2

3

4

5

Headache, dizziness, confusion

48 (15.6%)

23 (47.9%)

22 (45.8%)

3 (6.3%)

  

Blurred vision

3 (1.0%)

3 (100%)

    

Tremor

8 (2.6%)

3 (37.5%)

4 (50%)

1 (12.5%)

  

Neuralgia

2 (0.7%)

1 (50%)

1 (50%)

   

Seizure

6 (2.0%)

2 (33.3%)

2 (33.3%)

1 (16.7%)

1 (16.7%)

 

Pyramidal tract syndrome

1 (0.3%)

 

1 (100%)

   

Cerebellar syndrome

3 (1.0%)

 

2 (66.7%)

1 (33.3%)

  

Opsoclonus-myoclonus syndrome

1 (0.3%)

 

1 (100%)

   

Coma

1 (0.3%)

 

1 (100%)

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