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Table 3 Adjusted estimates for mean methylation level stratified by quartile of serum CRP concentration

From: Correlation between global methylation level of peripheral blood leukocytes and serum C reactive protein level modified by MTHFR polymorphism: a cross-sectional study

     95% confidence interval
MTHFR (rs1801133) CRP (mg/dL) N Estimated mean methylation (%)a Lower Upper
CT/TT 0.002–0.011 73 69.8 68.7 71.0
  0.012–0.023 59 70.5 69.2 71.7
  0.024–0.048 63 71.4 70.1 72.7
  0.049–0.491 69 71.6 70.4 72.8
CC 0.002–0.011 27 70.4 68.9 72.0
  0.012–0.023 30 71.3 69.8 72.8
  0.024–0.048 29 71.3 69.8 72.8
  0.049–0.491 23 70.1 68.4 71.8
  1. aAdjusted by age, BMI, smoking (never, former, current), exercise (none/week, 1–2 times/week, ≥3 times/week), drinking (non-drinker, sometimes, < 150 g/week, ≥150 g/week), and folate intake (quartile). Estimates were calculated with average values of continuous variables