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Table 3 Prevalence of MMTV like env sequence in human breast cancer samples and controls in published articles between 1995 and 2014 from different geographical location

From: Prevalence of Mouse Mammary Tumor Virus (MMTV)-like sequences in human breast cancer tissues and adjacent normal breast tissues in Saudi Arabia

Year

Geographic location

Breast cancer samples

Control samples

Reference

Number

MMTV-like env positivity no. (%)

Number

MMTV-like env positivity no. (%)

1995

USA

314

121 (38.5%)

136

(29 fibroadenoma and 107 reduction mammoplasty)

4 (2.9%)

[5]

2000

USA

72

27 (37%)

35

(25 negative biopsy, 5 reduction mammoplasty and 5 adjacent breast tissue)

0 (0%)

[7]

2001

USA

106

32 (30.1%)

106

(paired breast tissue)

1 (0.94)

[6]

2003

Australia

45 Caucasian Australian, 120, Vietnamese

41 Vietnamese- Australian

19 (42.2%) Caucasian Australian, 1(0.8%), Vietnamese

0 (0%) Vietnamese- Australian

111 Australian and 60 Vietnamese (normal breast tissues)

2 (1.8%) Australian and 0 (0%) Vietnamese

[17]

2004

Australia

128

50 (40%)

–

–

[43]

2004

Australia

136

+  13 male breast cancer

43 (32%)

+  8 (62%)

164

(111 normal breast tissue,25 fibroadenoma, 4 hyperplasia, 25 fibrocystic) +  52 male (gynecomastia)

15 (9%)

+  10 (19%)

[44]

2004

Tunisia

38

28 (73%)

–

–

[38]

2006

Italy

45

15 (33%)

40

(8 normal breast tissue, 4 blood from breast cancer patients, 20 other cancers and 8 blood from healthy blood donor)

0

[39]

2007

Mexico

119

5 (4.2%)

–

–

[45]

2008

Australia

50

28 (56%)

–

–

[10]

2008

Tunisia

122

17 (13.9%)

122

(adjacent breast tissue)

0 (0%)

[34]

2008

Japan

46

0 (0%)

3 benign breast tumor

0 (0%)

[35]

2010

Australia

74

33 (45%)

29

(reduction mammoplasty)

0 (0%)

[37]

2011

Australia

42

0 (0%)

–

–

[46]

2012

Australia

50

39 (78%)

40

(milk from normal lactating women)

8 (32%)

[9]

2012

Iran

50+  300 blood from breast cancer patient

0 (0%)

300

(blood from healthy donor)

0 (0%)

[36]

2013

Mexico

86

0 (0%)

65

(adjacent breast tissue)

0 (0%)

[47]

2013

Iran

40

0 (0%)

–

–

[48]

2014

Mexico

458

57 (12.4%)

458

(adjacent breast tissue)

72 (15.7%)

[33]

2014

Pakistan

80+  80 paired blood samples

16 (20%)

–

–

[40]

2014

Morocco

42

24 (57%)

18 (matched normal breast tissue from safety margins)

6 (33.3%)

[41]

2017

Pakistan

250 samples

29.3%

–

–

[49]

2017

Myanmar

58 samples

1 (1.7%)

–

–

[50]