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Table 2 Univariate and multivariate analysis for overall survival

From: Prognostic implications of polycomb proteins ezh2, suz12, and eed1 and histone modification by H3K27me3 in sarcoma

Variables Univariate Multivariate
5-yr OS P-value HR (95% CI) P-value
Sex (Male vs. Female) 49% vs. 48% 0.970   
Age (≥20 vs. < 20) 41% vs. 53% 0.690   
Stage(I or II vs. III or IV) 60% vs. 36% 0.020   
Histologic Grade (Grade 1 or 2 vs. Grade 3) 100% vs. 45% 0.043   
Tumor location (Axial vs. Extremity) 42% vs. 52% 0.389   
Initial metastasis (Yes vs. No) 16% vs. 55% 0.001 3.365 (1.295–8.745) 0.013
Surgery (Yes vs. No) 50% vs. 0% 0.045   
Margin status (R0 vs. R1 or R2) 59% vs. 32% 0.036   
EZH2 (non-high vs. high) 78% vs. 41% 0.026   
SUZ12 (non-high vs. high) 53% vs. 0% 0.001 29.069 (1.690–500.007) 0.020
EED1 (non-high vs. high) 67% vs. 44% 0.279   
H3K27me3 (non-high vs. high) 51% vs. 0% 0.009 3.743 (1.370–10.228) 0.010
All PRC2 (non-high vs. high) 52% vs. 0% 0.009   
  1. HR hazard ratio, CI, confidence interval
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