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Table 2 Univariate and multivariate analysis for overall survival

From: Prognostic implications of polycomb proteins ezh2, suz12, and eed1 and histone modification by H3K27me3 in sarcoma

Variables

Univariate

Multivariate

5-yr OS

P-value

HR (95% CI)

P-value

Sex (Male vs. Female)

49% vs. 48%

0.970

  

Age (≥20 vs. < 20)

41% vs. 53%

0.690

  

Stage(I or II vs. III or IV)

60% vs. 36%

0.020

  

Histologic Grade (Grade 1 or 2 vs. Grade 3)

100% vs. 45%

0.043

  

Tumor location (Axial vs. Extremity)

42% vs. 52%

0.389

  

Initial metastasis (Yes vs. No)

16% vs. 55%

0.001

3.365 (1.295–8.745)

0.013

Surgery (Yes vs. No)

50% vs. 0%

0.045

  

Margin status (R0 vs. R1 or R2)

59% vs. 32%

0.036

  

EZH2 (non-high vs. high)

78% vs. 41%

0.026

  

SUZ12 (non-high vs. high)

53% vs. 0%

0.001

29.069 (1.690–500.007)

0.020

EED1 (non-high vs. high)

67% vs. 44%

0.279

  

H3K27me3 (non-high vs. high)

51% vs. 0%

0.009

3.743 (1.370–10.228)

0.010

All PRC2 (non-high vs. high)

52% vs. 0%

0.009

  
  1. HR hazard ratio, CI, confidence interval