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Table 1 Relationship between MCM2, MCM6 and MCM7 expression and clinico-pathological characteristics in 175 HCC patients

From: MCM family in HCC: MCM6 indicates adverse tumor features and poor outcomes and promotes S/G2 cell cycle progression

  MCM2a MCM6a MCM7a
Variables Low High p Low High p Low High p
Age (years)    0.752    0.874    0.527
≤50 31 29   29 31   32 28  
> 50 56 59   58 57   55 60  
Sex    0.288    0.676    0.136
Female 10 16   14 12   9 17  
Male 77 72   73 76   78 71  
Tumor size (total diameter)    0.646    0.443    0.021
≤5 cm 37 34   38 33   43 28  
> 5 cm 50 54   49 55   44 60  
Tumor multiplicity    0.388    0.832    0.832
Single 77 73   74 76   74 76  
Multiple 10 15   13 12   13 12  
Tissue AFP    0.880    0.228    0.451
Low 44 43   39 48   46 41  
High 43 45   48 40   41 47  
Tissue Ki67    0.050    < 0.001    0.008
Low 50 37   62 25   52 35  
High 37 51   25 63   35 53  
Differentiation    0.057    < 0.001    0.259
Well 11 10   17 4   13 8  
Moderate 55 42   55 42   50 47  
Poor 21 36   15 42   24 33  
TNM stage    0.742    0.324    0.103
I 11 7   8 10   14 4  
II 37 37   43 31   38 36  
III 32 37   32 37   31 38  
IV 2 2   1 3   2 2  
  1. aHigh and low expression were divided by the median expression level
  2. Italic values indicate statistical significance