BMC Cancer

Table 1 Relationship between MCM2, MCM6 and MCM7 expression and clinico-pathological characteristics in 175 HCC patients

From: MCM family in HCC: MCM6 indicates adverse tumor features and poor outcomes and promotes S/G2 cell cycle progression

	MCM2^a			MCM6^a			MCM7^a
Variables	Low	High	p	Low	High	p	Low	High	p
Age (years)			0.752			0.874			0.527
≤50	31	29		29	31		32	28
> 50	56	59		58	57		55	60
Sex			0.288			0.676			0.136
Female	10	16		14	12		9	17
Male	77	72		73	76		78	71
Tumor size (total diameter)			0.646			0.443			0.021
≤5 cm	37	34		38	33		43	28
> 5 cm	50	54		49	55		44	60
Tumor multiplicity			0.388			0.832			0.832
Single	77	73		74	76		74	76
Multiple	10	15		13	12		13	12
Tissue AFP^†			0.880			0.228			0.451
Low	44	43		39	48		46	41
High	43	45		48	40		41	47
Tissue Ki67^†			0.050			< 0.001			0.008
Low	50	37		62	25		52	35
High	37	51		25	63		35	53
Differentiation			0.057			< 0.001			0.259
Well	11	10		17	4		13	8
Moderate	55	42		55	42		50	47
Poor	21	36		15	42		24	33
TNM stage			0.742			0.324			0.103
I	11	7		8	10		14	4
II	37	37		43	31		38	36
III	32	37		32	37		31	38
IV	2	2		1	3		2	2

^aHigh and low expression were divided by the median expression level
Italic values indicate statistical significance

Back to article page

ISSN: 1471-2407

Contact us

Submission enquiries: bmccancer@biomedcentral.com
General enquiries: ORSupport@springernature.com