Cycle 1
|
Day 1
|
Before administration
|
≤ 2 h.
|
10 min after the completion of administration
|
± 5 min.
|
Day 2
|
24 h after the completion of administration
|
± 1 h.
|
Day 4
|
72 h after the start of administration
|
± 2 h.
|
Day 8
|
168 h after the start of administration
|
± 3 h.
|
Day 15
|
336 h after the start of administration
|
± 3 h.
|
Cycle 2
|
Day 1
|
Before administration
|
≤ 2 h.
|
10 min after the completion of administration
|
± 5 min.
|
Day 2
|
24 h after the completion of administration
|
± 2 h.
|
Day 4
|
72 h after the start of administration
|
± 2 h.
|
Day 8
|
168 h after the start of administration
|
± 3 h.
|
Day 15
|
336 h after the start of administration
|
± 3 h.
|
Cycle 3
|
Day 1
| |
≤ 2 h.
|
–
|
Safety follow-up
|