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Fig. 2 | BMC Cancer

Fig. 2

From: Metabolomic profiling identifies distinct phenotypes for ASS1 positive and negative GBM

Fig. 2

Cross-validated scores, first predictive score (tcv[1]) based on the final OPLS models for the amino acid analysis from (a) the cell supernatant and (b) corresponding loadings (p[1]cv[1]) from the cell supernatant and (c) cross-validated scores (tcv[1]) from the cell pellet and (d) corresponding loadings (p[1]cv[1]) from the cell pellet. The score plots show an almost complete separation between ASS+ve cell lines (grey) and ASS-ve cell lines (black). The loadings bar-plots show the metabolites responsible for the cell line separation. The metabolites marked in grey are elevated in the ASS+ve cell lines and metabolites marked in black are elevated in the ASS1-ve cell lines. The metabolites marked with * are involved in the arginine biosynthetic pathway, and elevated predominantly in ASS+ve cell lines

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