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Fig. 1 | BMC Cancer

Fig. 1

From: Selective oestrogen receptor antagonists inhibit oesophageal cancer cell proliferation in vitro

Fig. 1

ER mRNA expression increases in oesophageal cancer. a Before-and-after plot demonstrates the expression of ESR1 (ERα) mRNA in normal mucosa and oesophageal tumour samples for individual patients with oesophageal cancer (N = 34). b Box and whisker plot demonstrates the overall expression of ESR1 (ERα) mRNA in normal mucosa and oesophageal tumour samples for 34 patients with oesophageal cancer. There is significant up-regulation of ESR1 (ERα) mRNA in oesophageal tumour samples in comparison to matched normal mucosal samples (*p = 0.035, Wilcoxon matched pairs signed ranked test).c Before-and-after plot demonstrates the expression of ESR2 (ERβ) mRNA in normal mucosa and oesophageal tumour samples for individual patients with oesophageal cancer (N = 34). d Box and whisker plot demonstrates the overall expression of ESR2 (ERβ) mRNA in normal mucosa and oesophageal tumour samples from 34 patients with oesophageal cancer. There is significant up-regulation of ESR2 (ERβ) mRNA in oesophageal tumour samples in comparison to matched normal mucosal samples (*p = 0.017, Wilcoxon matched pairs signed ranked test)

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