Table 2 BRCA 1/2 germline mutation prevalence by age group
n | BRCA1 | BRCA2 | BRCA1/2 | ||||
|---|---|---|---|---|---|---|---|
n | % (95%CI) | n | % (95%CI) | n | % (95%CI) | ||
Age group (years) | |||||||
20–29 | 85 | 28 | 32.9 (23.9–43.5) | 0 | 0.0 (0.0–4.3) | 28 | 32.9 (23.9–43.5) |
30–39 | 309 | 60 | 19.4 (15.4–24.2) | 3 | 1.0 (0.3–2.8) | 63 | 20.4 (16.3–25.2) |
40–49 | 216 | 22 | 10.2 (6.8–14.9) | 3 | 1.4 (0.5–4.0) | 25 | 11.6 (8.0–16.5) |
50–59 | 122 | 6 | 4.9 (2.3–10.3) | 1 | 0.8 (0.1–4.5) | 7 | 5.7 (2.8–11.4) |
60–69 | 58 | 2 | 3.4 (1.0–11.7) | 2 | 3.4 (1.0–11.7) | 4 | 6.9 (2.7–16.4) |
70–79 | 12 | 0 | 0.0 (0.0–24.2) | 0 | 0.0 (0.0–24.2) | 0 | 0.0 (0.0–24.2) |
TOTAL | 802 | 118 | 14.7 (12.4–17.3) | 9 | 1.1 (0.6–2.1) | 127 | 15.8 (13.5–18.5) |