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Table 2 BRCA 1/2 germline mutation prevalence by age group

From: Prevalence of pathogenic BRCA1/2 germline mutations among 802 women with unilateral triple-negative breast cancer without family cancer history

  n BRCA1 BRCA2 BRCA1/2
n % (95%CI) n % (95%CI) n % (95%CI)
Age group (years)
 20–29 85 28 32.9 (23.9–43.5) 0 0.0 (0.0–4.3) 28 32.9 (23.9–43.5)
 30–39 309 60 19.4 (15.4–24.2) 3 1.0 (0.3–2.8) 63 20.4 (16.3–25.2)
 40–49 216 22 10.2 (6.8–14.9) 3 1.4 (0.5–4.0) 25 11.6 (8.0–16.5)
 50–59 122 6 4.9 (2.3–10.3) 1 0.8 (0.1–4.5) 7 5.7 (2.8–11.4)
 60–69 58 2 3.4 (1.0–11.7) 2 3.4 (1.0–11.7) 4 6.9 (2.7–16.4)
 70–79 12 0 0.0 (0.0–24.2) 0 0.0 (0.0–24.2) 0 0.0 (0.0–24.2)
 TOTAL 802 118 14.7 (12.4–17.3) 9 1.1 (0.6–2.1) 127 15.8 (13.5–18.5)