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Fig. 2 | BMC Cancer

Fig. 2

From: Is RNASEL:p.Glu265* a modifier of early-onset breast cancer risk for carriers of high-risk mutations?

Fig. 2

Pedigrees of the families carrying (a) BRCA1:p.Glu1413Aspfs, (b) BRCA1:p.Leu2092Profs and (c) ATM:p.Val2424Glu. +: carriers of the pathogenic mutation; # and -: carriers and non-carriers of RNASEL:p.Glu265*, respectively; arrow: proband. Breast cancer is indicated by black filled symbols, and other cancers are indicated by quarter-filled symbols. Numbers within symbols represent multiple individuals

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