Skip to main content

Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Table 5 Copy number variations (CNVs) in cohorts 1 and 2 at AKAP containing loci

From: Exome sequencing of primary breast cancers with paired metastatic lesions reveals metastasis-enriched mutations in the A-kinase anchoring protein family (AKAPs)

   P1 P2 P3 P4 P5 P8 # Amp in cohort 2 # Del in cohort 2
Gene Chr region Primary Metastasis Primary Metastasis Primary Metastasis Primary Metastasis Primary Metastasis Primary Metastasis Primary Metastasis Primary Metastasis
AKAP1 17q22         amp      10 11   
AKAP5 14q23       del          0 1
AKAP6 14q12       del        4 5   
AKAP7 6q23.2 del del   del      del del    1 4 0 2
AKAP8 19q13.12         amp      6 9   1
AKAP11 13q14.11 del del     del       del 0 2   
AKAP12 6q25.1 del del   del      del del    0 2 2 3
  1. CNV in cohort 1 were determined by calculating the normalized read coverage at each SNP position for paired tumor and germline samples, then taking the log2 of the ratio of these numbers and recentering to zero (see also Additional file 4: Figure S1 and Additional file 3: Figure S2)