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Table 3 Association between LGR5 expression and 5-year RFS percentage by stratifying molecular subtype

From: LGR5 overexpression confers poor relapse-free survival in breast cancer patients

Protein expression Molecular subtype Total Percent First event (Recurrence and/or death) Percent
LGR5   126   13 9.0
 Low Non-TNBC 63 50.0 3 7.9
 Low TNBC 5 5.7 0 0.0
 High Non-TNBC 46 36.1 8 13.0
 High TNBC 12 8.2 2 16.7
β-catenin   119   13 10.9
 Low Non-TNBC 57 47.9 5 8.8
 Low TNBC 6 5.0 0 0.0
 High Non-TNBC 45 37.8 6 13.3
 High TNBC 11 9.2 2 18.2
LGR5/ β-catenin   102   11 10.8
 Low/ Low Non-TNBC 29 50.0 2 6.9
 Low/ High Non-TNBC 28 5.7 1 3.6
 High/ Low Non-TNBC 28 36.1 3 10.7
 High/ High Non-TNBC 17 8.2 5 29.4
LGR5/ β-catenin   17   2 11.8
 Low/ Low TNBC 4 23.5 0 0.0
 Low/ High TNBC 1 5.9 0 0.0
 High/ Low TNBC 2 11.8 0 0.0
 High/ High TNBC 10 58.8 2 20.0