Table 3 Association between LGR5 expression and 5-year RFS percentage by stratifying molecular subtype
From: LGR5 overexpression confers poor relapse-free survival in breast cancer patients
Protein expression | Molecular subtype | Total | Percent | First event (Recurrence and/or death) | Percent |
|---|---|---|---|---|---|
LGR5 | 126 | 13 | 9.0 | ||
Low | Non-TNBC | 63 | 50.0 | 3 | 7.9 |
Low | TNBC | 5 | 5.7 | 0 | 0.0 |
High | Non-TNBC | 46 | 36.1 | 8 | 13.0 |
High | TNBC | 12 | 8.2 | 2 | 16.7 |
β-catenin | 119 | 13 | 10.9 | ||
Low | Non-TNBC | 57 | 47.9 | 5 | 8.8 |
Low | TNBC | 6 | 5.0 | 0 | 0.0 |
High | Non-TNBC | 45 | 37.8 | 6 | 13.3 |
High | TNBC | 11 | 9.2 | 2 | 18.2 |
LGR5/ β-catenin | 102 | 11 | 10.8 | ||
Low/ Low | Non-TNBC | 29 | 50.0 | 2 | 6.9 |
Low/ High | Non-TNBC | 28 | 5.7 | 1 | 3.6 |
High/ Low | Non-TNBC | 28 | 36.1 | 3 | 10.7 |
High/ High | Non-TNBC | 17 | 8.2 | 5 | 29.4 |
LGR5/ β-catenin | 17 | 2 | 11.8 | ||
Low/ Low | TNBC | 4 | 23.5 | 0 | 0.0 |
Low/ High | TNBC | 1 | 5.9 | 0 | 0.0 |
High/ Low | TNBC | 2 | 11.8 | 0 | 0.0 |
High/ High | TNBC | 10 | 58.8 | 2 | 20.0 |